Use below settings when connecting using main ftp user though Dreamweaver :
- Ftp Host : For this just use your domain name. ( ie. ftp.domain.com, NO ftp:// )
- Host Directory : This should not be left blank, use 'public_html'
- Username : Your Cpanel user (which is also your main ftp user)
- Password : Your Cpanel password
Important Note : Host Directory for the main ftp user must be set to public_html in your Dreamweaver, or the files will go to the wrong directory.